Anti-GCS antibodies enable researchers to detect and measure the GCS antigen in biological samples. This target is a reported synonym of the UGCG gene, which encodes UDP-glucose ceramide glucosyltransferase. This protein is known to function in cell differentiation and epidermis development, among other biological roles. The human version of GCS has a canonical amino acid length of 394 residues and a protein mass of 44.9 kilodaltons. It is reported to be localized in the Golgi of cells and notably expressed in many tissues, such as the kidney and liver. GCS is a member of the Glycosyltransferase 2 protein family.