Anti-OPA3 antibodies are used in the immunodetection of the protein outer mitochondrial membrane lipid metabolism regulator OPA3. In humans, the canonical protein has a reported length of 179 amino acid residues and a mass of 20 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the OPA3 protein family, OPA3 is believed to play some role in mitochondrial processes. The OPA3 gene has been associated with the disease, 3-methylglutaconic aciduria. Synonyms for this target antigen include 3-methylglutaconic aciduria type III, OPA3 outer mitochondrial membrane lipid metabolism regulator, Optic atrophy 3 (Iraqi-Jewish 'optic atrophy plus'), and optic atrophy 3 protein. OPA3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of OPA3 antibodies have been mentioned in research publications and have associated citations. Western Blot and Immunohistochemistry are common applications for these antibodies.