Anti-LRIT3 antibodies are used in the immunodetection of the protein leucine rich repeat, Ig-like and transmembrane domains 3. In humans, the canonical protein has a reported length of 679 amino acid residues and a mass of 74.8 kDa. Its subcellular localization is in the cell projections and ER. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the outer plexiform layer (OPL) of the retina where it localizes to ON-bipolar cells. LRIT3 is reported to play a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells (By similarity). Synonyms for this target antigen include fibronectin type III, immunoglobulin and leucine rich repeat domains 4, leucine-rich repeat, immunoglobulin-like and transmembrane domains 3, and leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3. A number of LRIT3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry and Immunohistochemistry are also common applications.