Anti-DHFR2 antibodies are used in the immunodetection of the protein dihydrofolate reductase 2. In humans, the canonical protein has a reported length of 187 amino acid residues and a mass of 21.6 kDa. Its subcellular localization is in the mitochondria. It is reported to be expressed in numerous cell lines. A member of the Dihydrofolate reductase protein family, DHFR2 is known to be a key enzyme in folate metabolism. Synonyms for this target antigen include dihydrofolate reductase like 1, dihydrofolate reductase pseudogene 4, dihydrofolate reductase, mitochondrial, dihydrofolate reductase-like protein 1, and dihydrofolate reductase 2, mitochondrial. DHFR2 gene orthologs have been reported in the mouse, rat and chimpanzee species. A number of DHFR2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry and Immunofluorescence are also common applications.