Anti-coenzyme Q8A antibodies are used in the immunodetection of the protein encoded by the COQ8A gene. In humans, the canonical protein has a reported length of 647 amino acid residues and a mass of 72 kDa. Its subcellular localization is in the mitochondria. Alternative splicing is reported to yield 4 different isoforms for this protein. It is found to be widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle. A member of the ADCK protein kinase protein family, it is known to be an atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Other names for this target antigen include aarF domain-containing protein kinase 3, atypical kinase ADCK3, mitochondrial, chaperone activity of bc1 complex-like, mitochondrial, and atypical kinase COQ8A, mitochondrial.