Anti-DIRAS3 antibodies are used in the immunodetection of the protein DIRAS family GTPase 3. In humans, the canonical protein has a reported length of 229 amino acid residues and a mass of 25.9 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. It is a member of the Di-Ras protein family.
The DIRAS3 marker can be used to identify Gray Matter Splatter Neurons.* Synonyms for this target antigen include NOEY2, GTP-binding protein Di-Ras3, DIRAS family, GTP-binding RAS-like 3, distinct subgroup of the Ras family member 3, ras homolog gene family, member I, and ARHI. DIRAS3 gene orthologs have been reported in the mouse, bovine, frog and chimpanzee species. A number of DIRAS3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4