Anti-DTX3 antibodies are used in the immunodetection of the protein deltex E3 ubiquitin ligase 3. In humans, the canonical protein has a reported length of 347 amino acid residues and a mass of 38 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Deltex protein family, DTX3 is a reported regulator of notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Synonyms for this target antigen include RING finger protein 154, RING-type E3 ubiquitin transferase DTX3, deltex 3, E3 ubiquitin ligase, deltex homolog 3, protein deltex-3, and probable E3 ubiquitin-protein ligase DTX3. DTX3 gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. A number of DTX3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.