Anti-smoothelin like 1 antibodies are used for the immunodetection of the protein encoded by the SMTNL1 gene. In humans, the canonical protein has a reported length of 494 amino acid residues and a mass of 53 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be expressed in striated muscles, specifically in type 2a fibers. A member of the Smoothelin protein family, it is reported to play a role in the regulation of contractile properties of both striated and smooth muscles. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include smoothelin-like protein 1 and calponin homology-associated smooth muscle protein. Gene orthologs have been identified in the mouse, rat, bovine, chimpanzee and chicken species. Some smoothelin like 1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.