Anti-SELENOP antibodies are used in the immunodetection of the protein selenoprotein P. In humans, the canonical protein has a reported length of 381 amino acid residues and a mass of 43.2 kDa. It has been described to be a secreted protein. It is notably widely expressed in many tissue types. A member of the Selenoprotein P protein family, SELENOP is known to be involved with brain development and post-embryonic development. Post-translational modifications have been described, including phosphorylation and glycosylation.
The SELENOP marker can be used to identify Thymic Macrophages, Thymic Cortical Macrophages, and Thymic Medullary Macrophages.* Synonyms for this target antigen include SEPP, SEPP1, SeP, selenoprotein P, plasma, 1, and SELP. SELENOP gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SELENOP antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4