Anti-myosin heavy chain 2 antibodies are used for the immunodetection of the protein encoded by the MYH2 gene. In humans, the canonical protein has a reported length of 1941 amino acid residues and a mass of 223 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Myosin protein family, it is known to be involved with muscle contraction. The gene encoding this protein is implicated in Myopathy. Other names for this target antigen include IBM3, MYH2A, MYHSA2, MYHas8, MYPOP, MyHC-2A, MyHC-IIa, and CMYP6. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. Over 600 citations in the literature describe the use of myosin heavy chain 2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.