Anti-RAPGEF1 antibodies are used in the immunodetection of the protein Rap guanine nucleotide exchange factor 1. In humans, the canonical protein has a reported length of 1077 amino acid residues and a mass of 120.5 kDa. Its subcellular localization is in the endosome. Up to 4 different isoforms have been reported for this protein. It is widely expressed across many tissue types. RAPGEF1 is known to be involved with neuronal development. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include GRF2, Rap guanine nucleotide exchange factor (GEF) 1, guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene), and C3G. RAPGEF1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Rapgef1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.