Anti-EFEMP2 antibodies are used in the immunodetection of the protein EGF containing fibulin extracellular matrix protein 2. In humans, the canonical protein has a reported length of 443 amino acid residues and a mass of 49.4 kDa. Its subcellular localization is in the extracellular matrix and is secreted. It is notably expressed in the testis. A member of the Fibulin protein family, EFEMP2 is reported to play a crucial role in elastic fiber formation in tissue, and in the formation of ultrastructural connections between elastic laminae and smooth muscle cells in the aorta, therefore participates in terminal differentiation and maturation of smooth muscle cell (SMC) and in the mechanical properties and wall integrity maintenance of the aorta. Synonyms for this target antigen include FBLN4, MBP1, UPH1, EGF-containing fibulin-like extracellular matrix protein 2, EGF containing fibulin like extracellular matrix protein 2, and ARCL1B. A number of EFEMP2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.