Anti-CRYBG1 antibodies are used in the immunodetection of the protein crystallin beta-gamma domain containing 1. In humans, the canonical protein has a reported length of 1723 amino acid residues and a mass of 188.7 kDa. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Beta/gamma-crystallin protein family, CRYBG1 is believed to function as a suppressor of malignant melanoma.
The CRYBG1 marker can be used to identify Choroid Plexus Non-Neuronal Cells.* Synonyms for this target antigen include ST4, beta/gamma crystallin domain-containing protein 1, absent in melanoma 1 protein, beta-gamma crystallin domain containing 1, suppression of tumorigenicity 4 (malignant melanoma), and AIM1. CRYBG1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the CRYBG1 antibodies listed below. Immunocytochemistry and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4