Anti-CAVIN1 antibodies are used in the immunodetection of the protein caveolae associated protein 1. In humans, the canonical protein has a reported length of 390 amino acid residues and a mass of 43.5 kDa. Its subcellular localization is in the cell membrane, nucleus, mitochondria, ER, and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as in adipose tissue and breast. A member of the CAVIN protein family, CAVIN1 is known to play an important role in caveolae formation and organization. Post-translational modifications have been described, including ubiquitination, protein cleavage and phosphorylation. The CAVIN1 gene has been associated with the disease, Congenital generalized lipodystrophy. Synonyms for this target antigen include TTF-I interacting peptide 12, congenital generalized lipodystrophy 4, polymerase I and transcript release factor, and RNA polymerase I and transcript release factor. CAVIN1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.