Anti-GHRL antibodies are used in the immunodetection of the protein ghrelin and obestatin prepropeptide. In humans, the canonical protein has a reported length of 117 amino acid residues and a mass of 12.9 kDa. It has been described to be a secreted protein. Up to 6 different isoforms have been reported for this protein. It is reported to be highly expressed in the stomach. A member of the Motilin protein family, GHRL is known to be involved with cartilage development and dendrite development. Post-translational modifications have been described, including acetylation. The GHRL marker can be used to identify Pancreatic Endocrine Cells.* Synonyms for this target antigen include appetite-regulating hormone, In2c-preproghrelin, ghrelin, growth hormone secretagogue receptor ligand, ghrelin/obestatin preprohormone, and MTLRP. GHRL gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4