Anti-WDR81 antibodies are used in the immunodetection of the protein WD repeat domain 81. In humans, the canonical protein has a reported length of 1941 amino acid residues and a mass of 211.7 kDa. Its subcellular localization is in the membrane, cytoplasmic vesicles, mitochondria, lysosomes and cytoplasm. Up to 6 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the WD repeat WDR81 protein family, WDR81 is known to function as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. The WDR81 gene has been associated with the disease, Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome. Synonyms for this target antigen include WD repeat-containing protein 81 and protein phosphatase 1, regulatory subunit 166. Some WDR81 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunofluorescence is also a common application.