Anti-TYW1B antibodies are used in the immunodetection of the protein tRNA-yW synthesizing protein 1 homolog B. In humans, the canonical protein has a reported length of 668 amino acid residues and a mass of 76.9 kDa. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the TYW1 protein family, TYW1B is a suspected component of the wybutosine biosynthesis pathway. Synonyms for this target antigen include long intergenic non-protein coding RNA 69, radical S-adenosyl methionine and flavodoxin domain-containing protein 2, radical S-adenosyl methionine and flavodoxin domains 1, and S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B. TYW1B gene orthologs have been reported in the mouse and chimpanzee species. ELISA, Western Blot, and Immunohistochemistry are common applications for TYW1B antibodies.