Anti-RPP40 antibodies are used in the immunodetection of the protein ribonuclease P/MRP subunit p40. In humans, the canonical protein has a reported length of 363 amino acid residues and a mass of 41.8 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. RPP40 is known to be a component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Synonyms for this target antigen include bA428J1.3, ribonuclease P protein subunit p40, RNase P subunit 1, RNaseP protein p40, ribonuclease P (40 kD), and RNASEP1. RPP40 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. These RPP40 antibodies are widely used in Western Blot experiments, among other applications.