Anti-ATP10B antibodies are used in the immunodetection of the protein ATPase phospholipid transporting 10B (putative). In humans, the canonical protein has a reported length of 1461 amino acid residues and a mass of 165.4 kDa. Its subcellular localization is in the ER and lysosomes. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in predominantly in the brain structures including medulla oblongata, substantia nigra and basal ganglia. A member of the Cation transport ATPase (P-type) (TC 3.A.3) protein family, ATP10B is reported to be a catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of lysosome membranes. Synonyms for this target antigen include phospholipid-transporting ATPase VB, ATPase, class V, type 10B, P4-ATPase flippase complex alpha subunit ATP10B, probable phospholipid-transporting ATPase VB, and ATPVB. Indicated applications for ATP10B antibodies listed below include ELISA, Western Blot, and Immunohistochemistry.