Anti-PRXL2B antibodies are used in the immunodetection of the protein peroxiredoxin like 2B. In humans, the canonical protein has a reported length of 198 amino acid residues and a mass of 21.2 kDa. Its subcellular localization is in the cytoplasm. Up to 6 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Peroxiredoxin-like PRXL2 protein family, PRXL2B is known to catalyze the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Synonyms for this target antigen include family with sequence similarity 213 member B, prostamide/PG F synthase, prostamide/PGF synthase, thioredoxin-type PGF synthase, and prostamide/prostaglandin F synthase. PRXL2B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species.