Anti-butyrophilin like 8 antibodies are used in the immunodetection of the protein encoded by the BTNL8 gene. In humans, the canonical protein has a reported length of 500 amino acid residues and a mass of 56.7 kDa. Its subcellular localization is in the membrane. Alternative splicing is reported to yield 7 different isoforms for this protein. It is reported to be expressed in neutrophils. A member of the BTN/MOG protein family, it is believed to stimulate primary immune response. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include butyrophilin-like protein 8 and B7-H5 costimulatory molecule.