Anti-GAREM1 antibodies are used in the immunodetection of the protein GRB2 associated regulator of MAPK1 subtype 1. In humans, the canonical protein has a reported length of 876 amino acid residues and a mass of 97.2 kDa. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of a the GAREM protein family, GAREM1 is known to act as a adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include GRB2 associated regulator of MAPK1 1, GRB2 associated, regulator of MAPK1, GRB2-associated and regulator of MAPK1, and GRB2-associated and regulator of MAPK protein 1.