Anti-ataxin 3 like antibodies are used for the immunodetection of the protein encoded by the ATXN3L gene. In humans, the canonical protein has a reported length of 355 amino acid residues and a mass of 40.7 kDa. Its subcellular localization is in the nucleus. It is a type of deubiquitinating enzyme that cleaves both 'Lys-48'-linked and 'Lys-63'-linked poly-ubiquitin chains (in vitro). Other names for this target antigen include machado-Joseph disease protein 1-like, putative ataxin-3-like protein, and ataxin-3-like protein. Gene orthologs have been identified in the mouse, rat and chimpanzee species. Immunofluorescence is the most common application for the ataxin 3 like antibodies listed below. Western Blot and Immunohistochemistry are also common applications.