Anti-GABRG1 antibodies are used in the immunodetection of the protein gamma-aminobutyric acid type A receptor subunit gamma1. In humans, the canonical protein has a reported length of 465 amino acid residues and a mass of 53.6 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in the cerebral cortex, cerebellum, and caudate. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, GABRG1 is known to be involved with signal transduction pathways.
The GABRG1 marker can be used to identify Brain Medium Spiny Neurons and Gray Matter Medium Spiny Neurons.* Synonyms for this target antigen include GABA(A) receptor subunit gamma-1, GABA(A) receptor, gamma, gamma-1 polypeptide, gamma-aminobutyric acid (GABA) A receptor, gamma 1, and gamma-aminobutyric acid receptor subunit gamma-1. GABRG1 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of GABRG1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4