Anti-MYO3B antibodies are used in the immunodetection of the protein myosin IIIB. In humans, the canonical protein has a reported length of 1341 amino acid residues and a mass of 151.8 kDa. Its subcellular localization is in the cytoplasm. Up to 7 different isoforms have been reported for this protein. It is reported to be expressed in retina, kidney and testis. A member of the STE Ser/Thr protein kinase protein family, MYO3B is a suspected actin-based motor with a protein kinase activity. The MYO3B marker can be used to identify Midbrain-Derived Inhibitory Neurons.* MYO3B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the MYO3B antibodies listed below. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4