Anti-P2RY2 antibodies are used in the immunodetection of the protein purinergic receptor P2Y2. In humans, the canonical protein has a reported length of 377 amino acid residues and a mass of 42.3 kDa. Its subcellular localization is in the cell membrane. A member of the G-protein coupled receptor 1 protein family, P2RY2 is a known receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include P2RU1, P2U, P2U1, P2UR, P2Y2, P2Y2R, P2Y purinoceptor 2, and HP2U. P2RY2 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 70 citations in the literature describe the use of P2RY2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.