Anti-NAXD antibodies are used in the immunodetection of the protein NAD(P)HX dehydratase. In humans, the canonical protein has a reported length of 347 amino acid residues and a mass of 36.6 kDa. Its subcellular localization is in the mitochondria. Up to 4 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the adrenal gland and cerebral cortex. A member of the NnrD/CARKD protein family, NAXD is known to catalyze the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include ATP-dependent NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase, carbohydrate kinase domain containing, and ATP-dependent (S)-NAD(P)H-hydrate dehydratase. NAXD gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. These NAXD antibodies are widely used in Western Blot experiments, among other applications.