Anti-killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3 antibodies are used for the immunodetection of the protein encoded by the KIR2DS3 gene. In humans, the canonical protein has a reported length of 304 amino acid residues and a mass of 33.7 kDa. Its subcellular localization is in the cell membrane. A member of the Immunoglobulin protein superfamily, it is a known receptor on natural killer (NK) cells for HLA-C alleles. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include killer cell immunoglobulin-like receptor 2DS3, MHC class I NK cell receptor, NKAT-7, killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3, and NKAT7. Over 120 citations in the literature describe the use of killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3 antibodies in research. These antibodies are most commonly used in Flow Cytometry experiments, among other applications.