Anti-COL6A5 antibodies are used in the immunodetection of the protein collagen type VI alpha 5 chain. In humans, the canonical protein has a reported length of 2615 amino acid residues and a mass of 289.9 kDa. Its subcellular localization is in the extracellular matrix and is secreted. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in skin, followed by lung, small intestine, colon and testis. A member of the Type VI collagen protein family, COL6A5 is known to be involved with cell adhesion. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include collagen, type VI, alpha 5, collagen, type XXIX, alpha 1, von Willebrand factor A domain-containing protein 4, and collagen alpha-5(VI) chain. COL6A5 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Some COL6A5 antibodies may have been used in research and have associated citations. Immunocytochemistry is a widely used application for these antibodies. Western Blot and Immunofluorescence are also common applications.