Anti-Wnt family member 2B antibodies are used for the immunodetection of the protein encoded by the WNT2B gene. In humans, the canonical protein has a reported length of 391 amino acid residues and a mass of 43.8 kDa. Its subcellular localization is in the extracellular matrix and is secreted. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Wnt protein family, it is known to be involved with the Wnt signaling pathway and chondrocyte differentiation.
The Wnt family member 2B marker can be used to characterize Pericryptal Fibroblastic Sheath Cells.* Other names for this target antigen include protein Wnt-2b, XWNT2, Xenopus, homolog of, wingless-type MMTV integration site family, member 13, wingless-type MMTV integration site family, member 2B, and WNT13. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Wnt family member 2B antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4