Anti-LAMC3 antibodies are used in the immunodetection of the protein laminin subunit gamma 3. In humans, the canonical protein has a reported length of 1575 amino acid residues and a mass of 171.2 kDa. Its subcellular localization is in the extracellular matrix and is secreted. It is notably expressed in skin, heart, lung, and the reproductive tracts. LAMC3 is known to be involved with cell adhesion and eye development. Post-translational modifications have been described, including glycosylation.
The LAMC3 marker can be used to identify Lung Pericytes.* Synonyms for this target antigen include laminin, gamma 3, laminin-12 subunit gamma, laminin-14 subunit gamma, laminin-15 subunit gamma, and OCCM. LAMC3 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. A number of LAMC3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4