Anti-KIR2DL1 antibodies are used in the immunodetection of the protein killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1. In humans, the canonical protein has a reported length of 348 amino acid residues and a mass of 38.5 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is noted to be expressed by NK cells. A member of the Immunoglobulin protein superfamily, KIR2DL1 is a known receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include KIR-K64, KIR221, KIR2DL3, NKAT, NKAT-1, NKAT1, p58.1, and CD158A. Over 340 citations in the literature describe the use of KIR2DL1 antibodies in research. These antibodies are most commonly used in Flow Cytometry experiments, among other applications.