Anti-SLC19A1 antibodies are used in the immunodetection of the protein solute carrier family 19 member 1. In humans, the canonical protein has a reported length of 591 amino acid residues and a mass of 64.9 kDa. Its subcellular localization is in the cell membrane. Up to 3 different isoforms have been reported for this protein. It is notably expressed in the placenta, duodenum, cerebral cortex, and cerebellum. A member of the Reduced folate carrier (RFC) transporter (TC 2.A.48) protein family, SLC19A1 is a reported antiporter that mediates the import of reduced folates or a subset of cyclic dinucleotides, driven by the export of organic anions.
The SLC19A1 marker can be used to identify Brain Vascular Non-Neuronal Cells.* Synonyms for this target antigen include FOLT, IFC-1, IFC1, MEGAF, REFC, RFC, RFC1, and CHMD. SLC19A1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SLC19A1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4