Anti-DEXH-box helicase 58 antibodies are used for the immunodetection of the protein encoded by the DHX58 gene. In humans, the canonical protein has a reported length of 678 amino acid residues and a mass of 76.6 kDa. Its subcellular localization is in the cytoplasm. It is reported to be expressed in the testis, nerve and spleen. A member of the Helicase protein family, it is known to act as a regulator of RIGI and IFIH1/MDA5 mediated antiviral signaling. Other names for this target antigen include ATP-dependent helicase LGP2, DEXH (Asp-Glu-X-His) box polypeptide 58, RIG-I-like receptor 3, RIG-I-like receptor LGP2, RLR, and ATP-dependent RNA helicase DHX58. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of DEXH-box helicase 58 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.