Anti-QTRT1 antibodies are used in the immunodetection of the protein queuine tRNA-ribosyltransferase catalytic subunit 1. In humans, the canonical protein has a reported length of 403 amino acid residues and a mass of 44 kDa. Its subcellular localization is in the membrane, mitochondria, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the cerebral cortex, testis, and adrenal gland. A member of the Queuine tRNA-ribosyltransferase protein family, QTRT1 is a known catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Synonyms for this target antigen include TGT, catalytic subunit, guanine insertion enzyme, queuine tRNA-ribosyltransferase 1, tRNA-guanine transglycosylase, and TGT, 43-KD subunit. Western Blot is a widely used application for the QTRT1 antibodies listed below. In addition, ELISA is also a common application.