Anti-killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 antibodies are used for the immunodetection of the protein encoded by the KIR3DS1 gene. In humans, the canonical protein has a reported length of 382 amino acid residues and a mass of 42.5 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in NK and T-cell lines but not in B-lymphoblastoid cell lines or in a colon carcinoma cell line. A member of the Immunoglobulin protein superfamily, it is a known receptor on natural killer (NK) cells for MHC class I molecules. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include KIR-123FM, KIR-G1, NKAT-10, NKAT10, and CD158E2. Over 50 citations in the literature describe the use of killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 antibodies in research. These antibodies are most commonly used in Western Blot experiments, among other applications.