Anti-GABRQ antibodies are used in the immunodetection of the protein gamma-aminobutyric acid type A receptor subunit theta. In humans, the canonical protein has a reported length of 632 amino acid residues and a mass of 72 kDa. Its subcellular localization is in the cell membrane. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, GABRQ is known to be involved with chemical synaptic transmission and signal transduction pathways. Post-translational modifications have been described, including glycosylation.
The GABRQ marker can be used to identify Deep-Layer Corticothalamic And 6B Neurons, Gray Matter Neurons, and Hippocampal Gyrus CA1-3 Neurons.* Synonyms for this target antigen include GABA(A) receptor subunit theta, gamma-aminobutyric acid (GABA) A receptor, theta, gamma-aminobutyric acid type A receptor theta subunit, and gamma-aminobutyric acid receptor subunit theta. GABRQ gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Some GABRQ antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4