Anti-PDK3 antibodies are used in the immunodetection of the protein pyruvate dehydrogenase kinase 3. In humans, the canonical protein has a reported length of 406 amino acid residues and a mass of 46.9 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is found to be expressed in the heart, skeletal muscle, spinal cord, as well as fetal and adult brain. A member of the PDK/BCKDK protein kinase protein family, PDK3 is reported to inhibit pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Synonyms for this target antigen include GS1-358P8.4, pyruvate dehydrogenase kinase, isozyme 3, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, pyruvate dehydrogenase kinase, isoenzyme 3, and CMTX6. A number of PDK3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.