Anti-Wnt family member 16 antibodies are used for the immunodetection of the protein encoded by the WNT16 gene. In humans, the canonical protein has a reported length of 365 amino acid residues and a mass of 40.7 kDa. Its subcellular localization is in the extracellular matrix and is secreted. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Wnt protein family, it is known to be involved with the Wnt signaling pathway and keratinocyte differentiation. Post-translational modifications have been described, including glycosylation.
The Wnt family member 16 marker can be used to characterize Gray Matter MGE Interneurons.* Other names for this target antigen include wingless-type MMTV integration site family member 16b, wingless-type MMTV integration site family, member 16, and protein Wnt-16. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Wnt family member 16 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. In addition, Western Blot is also a common application.
*HuBMAP Human Reference Atlas v1.4