Anti-SLC17A6 antibodies are used in the immunodetection of the protein solute carrier family 17 member 6. In humans, the canonical protein has a reported length of 582 amino acid residues and a mass of 64.4 kDa. Its subcellular localization is in the cytoplasmic vesicles and cell membrane. It is reported to be highly expressed in the adult brain. A member of the Sodium/anion cotransporter protein family, SLC17A6 is reported to be a multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate. Post-translational modifications have been described, including glycosylation.
The SLC17A6 marker can be used to identify Retinal Ganglion Cells.* Synonyms for this target antigen include differentiation-associated BNPI, differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, differentiation-associated Na-dependent inorganic phosphate cotransporter, and vesicular glutamate transporter 2. SLC17A6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4