Anti-myosin light chain 9 antibodies are used for the immunodetection of the protein encoded by the MYL9 gene. In humans, the canonical protein has a reported length of 172 amino acid residues and a mass of 19.8 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is a reported myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation.
The myosin light chain 9 marker can be used to characterize Pericytes.* Other names for this target antigen include MLC-2C, MLC2, MMIHS4, MRLC1, MYRL2, myosin regulatory light polypeptide 9, 20 kDa myosin light chain, and LC20. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 2400 citations in the literature describe the use of myosin light chain 9 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4