Anti-THG1L antibodies are used in the immunodetection of the protein tRNA-histidine guanylyltransferase 1 like. In humans, the canonical protein has a reported length of 298 amino acid residues and a mass of 34.8 kDa. Its subcellular localization is in the mitochondria and cytoplasm. It is reported to be expressed in many tissues. A member of the TRNA(His) guanylyltransferase protein family, THG1L is known to be involved with the response to oxidative stress. The THG1L gene has been associated with the disease, Spinocerebellar ataxia. Synonyms for this target antigen include IHG-1, IHG1, SCAR28, THG1, hTHG1, probable tRNA(His) guanylyltransferase, induced by high glucose-1, and ICF45. THG1L gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some THG1L antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.