Anti-SLC9C1 antibodies are used in the immunodetection of the protein solute carrier family 9 member C1. In humans, the canonical protein has a reported length of 1177 amino acid residues and a mass of 135.2 kDa. Its subcellular localization is in the cell projections. Up to 2 different isoforms have been reported for this protein. A member of the Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) protein family, SLC9C1 is known to be involved with cell differentiation and potassium ion transport. Post-translational modifications have been described, including glycosylation.
The SLC9C1 marker can be used to identify Deep-Layer Corticothalamic And 6B Neurons and Deep-Layer Near-Projecting Neurons.* Synonyms for this target antigen include solute carrier family 9, member 10, solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1, sperm-specific Na(+)/H(+) exchanger, and sodium/hydrogen exchanger 10. SLC9C1 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4