Anti-CHRM5 antibodies are used in the immunodetection of the protein cholinergic receptor muscarinic 5. In humans, the canonical protein has a reported length of 532 amino acid residues and a mass of 60.1 kDa. Its subcellular localization is in the cell membrane. A member of the G-protein coupled receptor 1 protein family, CHRM5 is known to be involved with chemical synaptic transmission. Post-translational modifications have been described, including glycosylation. The CHRM5 marker can be used to identify Eccentric Medium Spiny Neurons.* Synonyms for this target antigen include muscarinic acetylcholine receptor M5, acetylcholine receptor, muscarinic 5, and HM5. CHRM5 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4