Anti-ARL3 antibodies are used in the immunodetection of the protein ADP ribosylation factor like GTPase 3. In humans, the canonical protein has a reported length of 182 amino acid residues and a mass of 20.5 kDa. Its subcellular localization is in the membrane, nucleus, Golgi, and cytoplasm. It is reported to be expressed in the retina. A member of the Arf protein family, ARL3 is reported to be a small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Synonyms for this target antigen include JBTS35, RP83, ADP-ribosylation factor-like protein 3, ADP-ribosylation factor-like 3, ARF-like 3, and ARFL3. ARL3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of ARL3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.