Anti-TNFRSF14 antibodies are used in the immunodetection of the protein TNF receptor superfamily member 14. In humans, the canonical protein has a reported length of 283 amino acid residues and a mass of 30.4 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is found to be widely expressed, with the highest expression in the lung, spleen and thymus. A member of the Tumor necrosis factor receptor protein superfamily, TNFRSF14 is a known receptor for four distinct ligands: The TNF superfamily members TNFSF14/LIGHT and homotrimeric LTA/lymphotoxin-alpha and the immunoglobulin superfamily members BTLA and CD160, altogether defining a complex stimulatory and inhibitory signaling network. Synonyms for this target antigen include CD270, HVEA, HVEM, LIGHTR, TR2, tumor necrosis factor receptor superfamily member 14, CD40-like protein, and ATAR. Over 150 citations in the literature describe the use of TNFRSF14 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Flow Cytometry are also common applications.