Anti-PLEKHG5 antibodies are used in the immunodetection of the protein pleckstrin homology and RhoGEF domain containing G5. In humans, the canonical protein has a reported length of 1006 amino acid residues and a mass of 111.2 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is reported to be highly expressed in the the peripheral nervous system and brain. PLEKHG5 is known to function as a guanine exchange factor (GEF) for RAB26 and thus regulates autophagy of synaptic vesicles in axon terminal of motoneurons (By similarity). Synonyms for this target antigen include PH domain-containing family G member 5, guanine nucleotide exchange factor 720, novel PH domain-containing protein, and pleckstrin homology domain-containing family G member 5. PLEKHG5 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some PLEKHG5 antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. Western Blot, Immunofluorescence, and Immunohistochemistry are also common applications.