Anti-CYP2F1 antibodies are used in the immunodetection of the protein cytochrome P450 family 2 subfamily F member 1. In humans, the canonical protein has a reported length of 491 amino acid residues and a mass of 55.5 kDa. Its subcellular localization is in the ER. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the lung. A member of the Cytochrome P450 protein family, CYP2F1 is suspected to be involved in the metabolism of various pneumotoxicants including naphthalene. The CYP2F1 marker can be used to identify Club Cells.* Synonyms for this target antigen include CYP2F, CYPIIF1, cytochrome P450 2F1, cytochrome P450, family 2, subfamily F, polypeptide 1, cytochrome P450, subfamily IIF, polypeptide 1, and C2F1. CYP2F1 gene orthologs have been reported in the mouse and rat species.
*HuBMAP Human Reference Atlas v1.4