Anti-Wnt family member 2 antibodies are used for the immunodetection of the protein encoded by the WNT2 gene. In humans, the canonical protein has a reported length of 360 amino acid residues and a mass of 40.4 kDa. Its subcellular localization is in the extracellular matrix and is secreted. It is reported to be expressed in the brain in the thalamus, in fetal and adult lung and in the placenta. A member of the Wnt protein family, it is known to be involved with the Wnt signaling pathway and cell to cell signaling.
The Wnt family member 2 marker can be used to characterize Type 1 Alveolar Fibroblast Cells.* Other names for this target antigen include IRP, protein Wnt-2, Int-1-related protein, epididymis secretory sperm binding protein, int-1-like protein 1, and INT1L1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Wnt family member 2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4