Anti-EIF4G3 antibodies are used in the immunodetection of the protein eukaryotic translation initiation factor 4 gamma 3. In humans, the canonical protein has a reported length of 1585 amino acid residues and a mass of 176.7 kDa. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Eukaryotic initiation factor 4G protein family, EIF4G3 is a known component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Synonyms for this target antigen include eIF-4-gamma 3, eIF-4-gamma II, and eIF4GII. EIF4G3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of EIF4G3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.